Choosing the right medication for your weight loss journey involves more than just selecting a name—it’s about finding the solution that best fits your body, lifestyle, and goals. At PURE Medical Spa, we offer two different routes for our medically supervised weight loss program: Semaglutide or Tirzepatide. While our expert providers guide you toward the best choice during your consultation, we believe that informed decisions lead to better outcomes. If you’re curious about the differences between Semaglutide vs Tirzepatide, we’re here to help you understand how each works, empowering you to make the decision that’s perfect for you.
Semaglutide vs Tirzepatide: The Basics
Semaglutide is a GLP-1 medication used for managing type 2 diabetes and weight loss. This type of medication is known as a receptor agonist, meaning it mimics the action of a natural substance in the body. In the case of Semaglutide, the hormone copied is glucagon-like peptide-1 (GLP-1).
Similarly, Tirzepatide is also a medication used to treat type 2 diabetes and for weight management; however, Tirzepatide targets the GLP-1 receptor, as well as the gastric inhibitory polypeptide (GIP) receptor. Therefore, making Tirzepatide a dual receptor agonist.
How Do These Medications Work for Weight Loss?
As GLP-1 receptor agonists, both medications stimulate the release of insulin, which helps regulate blood sugar levels and promotes feelings of fullness. This leads to a decrease in appetite and a reduction in overall calorie intake, resulting in weight loss.
With the ability to target a second hormone, Tirzepatide helps further enhance feelings of fullness and improve blood sugar control, potentially leading to even greater weight loss.
Side Effects
Semaglutide and Tirzepatide are generally safe and well-tolerated but, some may experience mild side effects like:
- Gastrointestinal Issues:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain
- Other Side Effects:
- Reduced appetite
- Headache
- Fatigue
- Dizziness
- Indigestion
- Gastroesophageal reflux disease (GERD)
- Injection site reactions
It’s important to note that these side effects are usually mild and temporary, often subsiding as your body adjusts to the medication.
Dosage
Semaglutide
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Starting Dose: 0.25 mg once weekly, administered subcutaneously (under the skin).
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Gradual Dose Increase: The dose is gradually increased over several weeks to minimize potential side effects.
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Maintenance Dose: The typical maintenance dose is 2 mg once weekly. However, some individuals may require a higher dose of 3 mg once weekly for optimal weight control.
Tirzepatide
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Starting Dose: 2.5 mg once weekly, administered subcutaneously.
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Gradual Dose Increase: Similar to Semaglutide, the dose is gradually increased to minimize side effects.
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Available Doses: Tirzepatide is available in doses of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. Your healthcare provider will determine the appropriate dose for you based on your individual needs and response to treatment.
Cost of Semaglutide vs Tirzepatide
Pricing varies depending on several factors, but at PURE we have three different options based on your needs.
1 Singular Injection (No Vitamin Injection Included)
- Semaglutide: $87.50
- Tirzepatide: $123.75
Monthly Package (4 GLP-1 Injections & 4 Complimentary Vitamin Injections)
- Semaglutide: $350
- Tirzepatide: $495
16 Week Package (16 GLP-1 Injections & 16 Complementary Vitamin Injections)
- Semaglutide: $1,300
- Tirzepatide: $1,880
Which is right for you: Semaglutide or Tirzepatide?
While both medications are highly effective for weight loss, Tirzepatide has been shown to produce slightly more significant results in clinical trials. However, the choice between the two often depends on individual factors such as medical history, personal preferences, and cost considerations.
Consulting a medical professional is essential before beginning any GLP-1 medication. At PURE, we recognize that achieving sustainable weight loss involves a comprehensive approach. That’s why we offer personalized guidance on nutrition, exercise, and lifestyle changes to enhance your treatment. Our dedicated team will help you select the appropriate medication and build lasting healthy habits that support your long-term success beyond your initial weight loss goals.